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July 23, 2017 at 06:34 PM EDT

As The Last Ship prepares shove off on its fourth season next month, TNT has unveiled a new trailer for the upcoming chapter of the post-apocalyptic drama.

First screened at Comic-Con in San Diego, the two-minute video finds protagonist Tom Chandler (Eric Dane) once again compelled to help save what’s left of humanity — this time because the devastating Red Flu has mutated and is blighting crops all over the globe.

“You wanted to disappear and you did,” Chandler is told. “But the world is in trouble again.”

The only hope lies in an ancient palm seed with proven immunity to the disease, but obtaining a sample won’t be easy. Watch the trailer above for more.

The Last Ship returns Aug. 20.

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