20 of our favorite pairs of fictional best friends

Bill (Alex Winter) and Ted's (Keanu Reeves) friendship stays true from Ancient Greece to the wild West, because they adhere to the two primary tenets of the Wyld Stallyns life: Be excellent to each other, and party on, dudes.

There are friends you go on a road trip with, and there are friends you keep going with. Thelma (Geena Davis) and Louise (Susan Sarandon) keep going.

Never was there a BFF love like Leslie's (Amy Poehler) for Ann (Rashida Jones), poetic and noble land-mermaid. Nor could anyone ever be a better pal to Leslie than Ann, opalescent tree shark. In conclusion, we know that true beautiful friendship can really exist in this otherwise cold dark world because we have witnessed it between Leslie and Ann, rainbow-infused space unicorn.

Woody himself said (sang) it best: You've got a friend in me…

The most fabulous thing about Patsy (Joanna Lumley) and Edina (Jennifer Saunders)? Their long-lasting friendship. Stay glam!

Nothing bonds a pair of high-flying bros (Tom Cruise and Anthony Edwards) like feeling the need — the need for speed.

Duh, they're both named after famous singers of the past who now do infomercials. Obviously Cher (Alicia Silverstone) and Dionne (Stacey Dash) are iconic BFFs.

The Rosencrantz and Guildenstern of the African jungle get along so well due in part, of course, to their famous problem-free philosophy.

Friendship doesn't come truer than Meredith (Ellen Pompeo) and Cristina's (Sandra Oh). That's what it means to be someone's person.

Just edging out Rachel (Jennifer Aniston) and Monica (Courteney Cox) are their across-the-hall neighbors (Matthew Perry and Matt LeBlanc), an undeniable duo of recliner-loving, foosball-playing chick-and-duck owners.

Whether it's shamelessly stalking celebrities or stuffing a conveyor belt of chocolates in their mouths, there's no ill-fated humiliation that these ladies (Lucille Ball and Vivian Vance) can't survive together.

F is for friends who do stuff together!

While Lilly (Heather Matarazzo) did briefly threaten to throw her charm bracelet with the sacred friendship charm into the dirt, we never doubted their connection. She kept Mia's (Anne Hathaway) royal secret! Do you know how hard it is to have a cable show and keep a secret?

"I made a promise, Mr. Frodo. A promise. 'Don't you leave him, Samwise Gamgee.' And I don't mean to. I don't mean to."

Forget about the Post-It notes, have you seen that dance routine?

Velma may be the brains and Fred the brawn of this crew of mystery-solving meddling kids, but the nervous duo of Scooby and his best pal (and bringer of Scooby snacks) Shaggy are the group's beating heart.

No matter what conniving guys they encounter or transcontinental showgirl hijinks they get into, this pair of little girls (Marilyn Monroe and Jane Russell) from Little Rock always comes out on top because they've got each other.

Nothing embarrassing about it: These dorky dudes (Michael Cera and Jonah Hill) love each other. Why don't they say that every day? Why can't they say it more often?

Break out the tissues. Did you ever know that you're my hero?

This pair of besties (Zach Braff and Donald Faison) practically invented the TV bromance. Now EEEEEAGLEEEE!