'Annihilation' costars Natalie Portman and Jennifer Jason Leigh
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Stars Wars and Inside Llewyn Davis actor Oscar Isaac has described his new science fiction film Annihilation (out Feb. 23, 2018) as “very weird and very beautiful.” Directed by Alex Garland, (who previously worked with Isaac on 2015’s Ex Machina) this adaptation of Jeff VanderMeer’s novel stars Natalie Portman as a biologist who joins an expedition to a mysterious site known as Area X, while also seeking answers about the disappearance of her husband (Isaac). The cast also includes Jennifer Jason Leigh, Tessa Thompson, and Gina Rodriguez.

“I’ve not had the pleasure of seeing it yet,” Isaac recently told EW, on a day off from playing the lead in Hamlet at New York’s Public Theater. “But I am certain that it will be very weird and very beautiful. You know, Alex Garland makes completely unique things, and he’s such a visionary, and I think it’s going to be a very powerful film. Maybe not for everyone — but that’s what’s amazing about working with artists like the Coens or Alex Garland, is that they follow their own creative impulses, and that’s, at the end of the day, how they make their decisions, following their own artistry and not making it all about things on the outside, and what’s going to please everyone. It’s so special to get to work with people like that.”

Isaac will next be seen alongside Matt Damon and Julianne Moore in the George Clooney-directed Suburbicon (out Oct. 27). Watch the trailer for that film, above.

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