Tom Hanks: 25 Most Memorable Roles

Know what Hanks was doing before he became the revered Academy Award-winning actor he is today? He was dragging around on TV in this cult buddy comedy that found him and Scolari as two pals who, after being kicked out of their apartment building, dressed as ladies so they could stay in an all-girls boarding house.

The Tom Wolfe novel was an intelligent, potent character study of the Wall Street types, racism, and social hierarchy of New York City in the '80s. So how do you whittle down 500-plus pages of a book for the big screen? You don't. The Brian De Palma-directed movie, costarring Tom Hanks, Bruce Willis, John Hancock, and Saul Rubinek as the four interweaving characters, lacked Wolfe's complexity and introspection.—Youyoung Lee

Hate on Ron Howard's adaptation of Dan Brown's runaway best-seller all you want, but you can't deny that Paul Bettany makes one scary albino. Even we won't bother trying to defend Tom Hanks' hair, though.