By Missy Schwartz
December 18, 2018 at 02:22 PM EST

“For me it was just something to do,” Penny Marshall said in 1996, reflecting on how she transitioned from acting to directing. “If I failed, I had my excuse: I was an actress, not a director.”

It turned out that Marshall — whom EW can confirm died on Monday night due to complications from diabetes at the age of 75 — needn’t have worried. In 1988, with Big, she became the first woman in Hollywood history to direct a movie that grossed more than $100 million at the box office. Two years later, her drama Awakenings earned a Oscar nomination for Best Picture. And in 1992, she topped $100 million again with A League of Their Own.

Harry Langdon/Getty Images

Born into an Italian-American family in the Bronx, Carole Penny Marshall briefly attended the University of New Mexico (where she met her first husband, Michael Henry) before joining her older brother Garry in Los Angeles in 1967. She landed her first notable big-screen role in the 1968 Debbie Reynolds-James Garner comedy How Sweet It Is, which the elder Marshall co-wrote. But over the next few years, she struggled to find work, often weathering hurtful criticism about her looks. “I wasn’t perky, and it was the years of Sally Field and The Flying Nun,” she once said. When she booked a 1970s TV commercial for Head & Shoulders shampoo, she played the plain Jane opposite Farrah Fawcett’s bubbly blonde.

But Marshall’s luck soon changed when her brother cast her in two television series that he produced: First came The Odd Couple, in which she appeared as Oscar Madison’s (Jack Klugman) secretary, Myrna Turner, from 1972-74; then Happy Days in 1975, where she launched the character that would make her a TV icon: Laverne DeFazio. The wisecracking tomboy and her perky roommate, Shirley Feeney (played by Cindy Williams), were such hits with the audience that the following year, ABC gave them their own show, Laverne & Shirley. The series, which chronicled the adventures of the two Milwaukee brewery workers, is now one of the most beloved sitcoms in TV history. (In 2007, TV Land announced they would reunite for a new series, a buddy comedy called Penny and Cindy. Unfortunately, the project never got off the ground.)

Over Laverne & Shirley‘s eight-year run, Marshall was nominated for three Golden Globes. And in an indication of things to come, she directed four episodes. And by the time she made her feature directorial debut with Jumpin’ Jack Flash in 1986, she had more or less retired as an actress. (She had also divorced her second husband, the filmmaker Rob Reiner, with whom she raised Tracy, her daughter from her marriage with Henry.) Though the films she directed after A League of Their Own — Renaissance Man, The Preacher’s Wife, and Riding in Cars With Boys — failed to match her earlier box office success, Marshall continued to collaborate with her filmmaker friends, producing Ron Howard’s Cinderella Man and Nora Ephron’s Bewitched, both in 2005.

A lifelong sports fan with an extensive collective of sports memorabilia, Marshall spent much of her later years cheering on her beloved L.A. Lakers and New York Yankees. Whether courtside or behind the dugout, she could be seen winning fellow fans over with that infectious Penny Marshall smile, her trademark tinted glasses sitting on the bridge of her nose.

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