By Ariana Bacle
Updated January 04, 2015 at 04:14 PM EST
Rex Brown/Getty Images

Stuart Scott, an anchor on ESPN’s SportsCenter, has died after a years-long battle with cancer. He was 49.

Scott joined the network in 1993 when ESPN2 launched. He went on to become a main anchor for ESPN’s SportsCenter, where catchphrases like “Boo-ya!” became his signature — and where he became one of the most recognizable faces in sports journalism.

“ESPN and everyone in the sports world have lost a true friend and a uniquely inspirational figure in Stuart Scott,” ESPN president John Skipper said in a statement. “Who engages in mixed martial arts training in the midst of chemotherapy treatments? Who leaves a hospital procedure to return to the set? His energetic and unwavering devotion to his family and to his work while fighting the battle of his life left us in awe, and he leaves a void that can never be replaced.”

Scott was honored for his contributions to the sports world on July 16 when he received the Jimmy V Perseverance Award at the 2014 ESPYs. His acceptance speech was prefaced with a video chronicling Scott’s life with cancer (he was diagnosed in 2007) and featured interviews with friends who praised Scott’s unwillingness to give up and his unwavering work ethic.

In his acceptance speech for the award, Scott addressed the possibility of death. “When you die, it does not mean that you lose to cancer,” he said. “You beat cancer by how you live, why you live, and in the manner in which you live.”

Scott is survived by two daughters, Taelor and Sydni.