Credit: YouTube/razorstarzz

Hollywood’s strangest duo is at it again: Johnny Depp appeared onstage at a Marilyn Manson show Friday night to play guitar.

Depp and Manson shared the stage back in 2012 at the RevolverGolden Gods Awards, where they played a cover of Eurythmics’ “Sweet Dreams (Are Made of This).” Soon after, they collaborated again for a cover of Carly Simon’s “You’re So Vain” that appeared as a bonus track on Manson’s 2012 album, Born Villain.

For Manson’s Halloween show, Depp jumped onstage to play guitar for “The Beautiful People” while Manson sang lead vocals. Watch a clip of the performance over at the Daily Mail.