By Ariana Bacle
Updated February 27, 2014 at 04:00 PM EST
Paul Morigi/WireImage

Seth Rogen isn’t all stoner comedies and “Bound 2” parodies. The self-described “man-child” put on a suit and tie yesterday to speak in front of the Senate about promoting Alzheimer’s education.

This wasn’t the first time Rogen has spoken out about Alzheimer’s. In 2011, he and his wife Lauren Miller sat down with Larry King to discuss the disease. Miller’s mom was diagnosed with early onset Alzheimer’s in her mid-fifties and, now in her sixties, is unable to perform most basic functions. Seeing the effects of Alzheimer’s on his mother-in-law has made Rogen an outspoken supporter of research, going as far as to start a charity with Miller.

Their organization, Hilarity for Charity, puts on events that include performances by comedy greats like Aziz Ansari and Patton Oswalt. The money raised by these events goes to families struggling with the disease and to research.

On Wednesday, Rogen went to the Senate to further promote the need for Alzheimer’s awareness and research. He delivered a 6-minute opening statement that included both jokes — “I came here today for a few reasons: One, I’m a huge House of Cards fan” — and some powerful sincerity. “Americans whisper the word ‘Alzheimer’s’ because their government whispers the word ‘Alzheimer’s,’ and although a whisper is better than the silence that the Alzheimer’s community has been facing for decades, it’s still not enough,” Rogen said at one point. “I dream of a day when my charity is no longer necessary and I can go back to being the lazy, self-involved man-child I was meant to be.” Can’t argue with that.

Watch Rogen’s full opening statement below: