By James Hibberd
Updated November 08, 2012 at 06:35 PM EST

Even if you’re not a Whitney Cummings fan, you gotta admit she sure knows how to promote a talk show.

In the first promo for her upcoming weekly E! series, the comedian takes on actress Kristen Stewart. Cummings notes how her series and Stewart’s final Twilight movie both premiere in November, then says, “[It’s] a big month for fans of cold-blooded pale bitches who’re clinically depressed and cheat on their boyfriends.”

Love You, Mean It With Whitney Cummings premieres Nov 28 on E! at 10:30 p.m following The Soup. I’m guessing her first guest probably isn’t Kristen Stewart. Also, Cummings’ sitcom Whitney returns Nov. 14 to NBC). Here’s the preview: