By Adam B. Vary
April 23, 2012 at 12:00 PM EDT
Tammie Arroyo/AP

• Jennifer Lawrence is eyeing the starring role for The Glass Castle, based on gossip columnist Jeanette Walls‘ 2005 family memoir. Lionsgate acquired the rights to the book, and Marti Noxon (I Am Number FourBuffy the Vampire Slayer) is penning the screenplay. The only arrows involved will most likely be verbal. [Deadline]

• Mel Gibson is in serious talks to take on a supporting role in Machete Kills, director Robert Rodriguez‘s sequel to his 2010 grindhouse thriller Machete with star Danny Trejo. [Deadline]

• Speaking of rugged leading men/media lightning rods aiming for a role several slots down on the call sheet, Sean Penn is negotiating to join Ben Stiller‘s remake of The Secret Life of Walter Mitty, for a key supporting part. Stiller is starring in the title role as well as directing, alongside Kristen WiigAdam ScottShirley MacLaine, and Patton Oswalt. [Deadline]

Jessica Chastain is in talks for Iron Man 3, to play a brilliant scientist opposite Tony Stark (Robert Downey, Jr.) — possibly a rival for his affections from Gwyneth Paltrow‘s Pepper Potts? [Deadline]

• Toni Collette and Dev Patel have signed onto Defiant, a thriller about honor killing in India. [Deadline]

• Melissa Leo will play Shia LaBeouf‘s mother in the crime romance The Necessary Death of Charlie Countryman. Til Schweiger (Inglorious Basterds) has also signed on to play a Serbian gangster. [Deadline, Variety]

• Gina Carano, the one-time American Gladiator and star of this year’s Steven Soderbergh thriller Haywire, is in talks to step aboard Fast & Furious 6. No word on the role, but it will likely involve chamber room tea settings and dense witticisms about oil prices butt kicking. [THR]

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