By Mandi Bierly
February 22, 2012 at 03:23 PM EST

Nothing makes an audience perk up like Jennifer Aniston talking about running topless. Aniston stopped by her friend Chelsea Handler’s show Chelsea Lately to dish about her new movie Wanderlust and the intimate conversation didn’t stop there. We also found out what it’s like to act opposite someone wearing a prosthetic penis. (SPOILER: After about 20 minutes, you find yourself comfortable enough to investigate it and have a conversation while a makeup artist kneels down to give your costar a touch-up.) Watch their chat below. 

Read more:

‘Wanderlust’ director David Wain on ‘Wainy Days’ premiere

Paul Rudd talks about going nude