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Film and TV actress Marcia Gay Harden has landed a lead role in an NBC comedy pilot.

The Damages and Mystic River star was cast in Isabel, about a “normal middle-class family that wrestles with the challenges of everyday life while raising a daughter (Sophia Mitri Schloss from Grimm) who has magical qualities.” Harden plays the family matriarch.

Isabel is one of five pilots ordered by NBC in recent months, with more to come in the next couple weeks. Howard Busgang (The Closer) and Tom Nursall (Single White Spenny) are the showrunners.