By Kate Ward
Updated January 21, 2011 at 05:21 PM EST

When two of America’s most powerful women collide: Michelle Obama is set to appear on The Oprah Winfrey Show, according to the Associated Press. The first lady will return to Chicago — her hometown — for the interview, set to air Thursday. Among other topics, Obama will speak to the talk show maven about supporting military families.

Read more:

Piers Morgan interviews Oprah on CNN: Larry King? Who’s Larry King?