By Nicole Sperling
Updated September 30, 2010 at 11:27 PM EDT

Emma Thompson, who most recently reprised her role as Nanny McPhee, is in talks to join Will Smith and team for Men In Black III. The 51-year old actress would play the head of the MIB operation, should the deal go through.

Thompson is no stranger to the tent pole, having played Professor Trelawney in the Harry Potter movies. Men in Black III is scheduled to go before cameras in November with Barry Sonnenfeld returning to direct a script by Etan Cohen (Tropic Thunder) . The 3-D movie is already slated to bow Memorial Day weekend 2012.