September 10, 2010 at 04:00 AM EDT

”The theme of the season is rebirth,” declares creator Shonda Rhimes, referring to the season-ending bloodbath that turned Seattle Grace into a war zone. To that end, we’ll discover Cristina (Sandra Oh) and Owen (Kevin McKidd) are married. Derek (Patrick Dempsey), meanwhile, will be experiencing the kind of prolonged ”adrenaline rush one gets after facing death and surviving, [which] manifests itself in a lot of sex with Meredith [Ellen Pompeo].” The fun ends, however, when he finds out that on the day of the massacre, Mer learned she was pregnant and suffered a miscarriage. Elsewhere in season 7, Callie (Sara Ramirez) and Arizona (Jessica Capshaw) will deal with a career-related obstacle, Teddy (Kim Raver) will strike up a romance with the new trauma counselor (Mercy‘s James Tupper), and Alex (Justin Chambers) will get closure with Izzie, whether Katherine Heigl returns to wrap up the story line or not. SEPT. 23

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