By EW Staff
Updated August 13, 2010 at 04:00 AM EDT
David James

STARRING Jake Gyllenhaal, Anne Hathaway, Hank Azaria, Oliver Platt
WRITTEN BY Charles Randolph, Edward Zwick, Marshall Herskovitz
DIRECTED BY Edward Zwick

The idea of a heartthrob like Jake Gyllenhaal playing a Viagra salesman may sound a bit…redundant. But in Love and Other Drugs, loosely based on Jamie Reidy’s memoir Hard Sell, the actor stars as a pharmaceutical peddler at the mid-’90s height of Little Blue Pill mania who learns there’s no substitute for the real drug — love — which comes in the free-spirited form of Anne Hathaway. ”Jake and I met years ago,” says director Edward Zwick (Defiance). ”I had a chance to see this funny, antic side of him audiences haven’t seen yet.” With a short shooting schedule, Zwick says he was lucky his two stars already knew each other, from 2005’s Brokeback Mountain. ”That chemistry definitely helped,” says Zwick, ”because they had to be very comfortable and brave with each other. There’s some real, um, intimacy in the film.” Let’s just hope that intimacy doesn’t cause headaches or dizziness or last for more than four hours.