By Mandi Bierly
Updated June 02, 2010 at 06:29 PM EDT

Image Credit: Jon Kopaloff/FilmMagic.comPeople often get down on Michael Cera for playing the same kind of character on repeat. Are there actors who tweak the mold just enough to escape criticism/audience fatigue? I’d nominate Paul Rudd, who’s just signed on to star in My Idiot Brother. According to The Hollywood Reporter, “Brother sees Rudd playing an idealist dealing with his overbearing mother who crashes into the homes of his three ambitious sisters and, in succession, brings truth, happiness, and a sunny disposition into their lives while also wreaking havoc.” Rudd’s sweet spot is the matured man-child who’s struggling with a next step: Role Models, I Love You, Man. He has a good eye for spotting worthwhile, comedic journeys.

Granted, we don’t know much about his character’s sisters — other than they’re “ambitious” and yet to be cast — but who would you like to see play his siblings? In my dream world, they’re Lauren Graham, Parker Posey, and, if one of the sisters needs to be much younger than him, Parks and Recreation‘s Aubrey Plaza or Up in the Air‘s Anna Kendrick. Your picks?