By Tim Stack
Updated March 01, 2010 at 05:01 AM EST

Shrek Forever After, the final film in the animated franchise, will open the 2010 Tribeca Film Festival on April 21. The film, which features the voices of Mike Myers, Cameron Diaz, Eddie Murphy and Antonio Banderas, is the first of the Shrek films to be presented in 3D. Shrek Forever After will open nationwide in theaters on May 21, 2010.