By Adam Markovitz
Updated January 05, 2010 at 10:56 PM EST

Vince Vaughn (Couples Retreat) will star in an untitled dramedy directed by Ron Howard, according to The Hollywood Reporter. The movie, scripted by Alan Loeb (Wall Street 2: Money Never Sleeps) from an idea by Vaughn and producer Brian Grazer, will follow a man who discovers that his best friend’s wife is cheating. Shooting could begin as early as next spring.

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