Australian actress Mia Wasikowska has scored the female lead role in Restless, director Gus Van Sant’s follow-up to Milk, has learned. Wasikowska, who’s perhaps best known as suicidal gymnast Sophie on HBO’s In Treatment, will appear as Alice in Tim Burton’s Alice in Wonderland next year. In Restless, written by first-time screenwriter Jason Lew, Wasikowska will play Annabel Cotton, a terminally ill 16-year-old who falls in love with a death-obsessed teenage boy. Ron Howard and his daughter Bryce Dallas Howard are co-producing the film for Columbia Pictures.