By Adam B. Vary
Updated June 06, 2009 at 09:40 PM EDT

The Hangover tossed back an estimated $16.5 million in box office receipts on Friday, according to Box Office Mojo, positioning the R-rated worst-night-in-Vegas-ever comedy to win as much $50 million for the weekend and the title of the summer’s first official sleeper hit. Disney/Pixar’s Up fared well too, earning an expected $13.5 million for second place. The Will Ferrell comedy Land of the Lost, based on the wildly popular 1970s kids TV show, landed at third place with $7.2 million. The weekend’s other new wide release, My Life in Ruins, starring My Big Fat Greek Wedding‘s Nia Vardalos, bagged just $1.1 million for ninth place. Friday’s figures are below, and check back here on Sunday for the complete weekend figures in EW’s Box Office Report.

1. The Hangover — $16,535,000
2. Up — $13,500,000
3. Land of the Lost — $7,218,000
4. Night at the Museum: Battle of the Smithsonian — $4,550,000
5. Drag Me to Hell — $2,573,000