By EW Staff
Updated January 09, 2008 at 05:00 AM EST

9-9:30PM · CBS · Returns Sept. 22

What are the dudes up to in year 6 of the Emmy-nominated comedy? Well, Charlie (Charlie Sheen) may be a dad! Or so it seems in the premiere, when he meets an old girlfriend (guest star Rena Sofer) with a child who’s a carbon copy of Charlie. Speaking of young ‘uns, Jake (Angus T. Jones) is now — gasp! — 14. ”We’re doing an episode where Jake gets hammered,” says creator Chuck Lorre. How will CBS’ standards and practices department feel about this? ”They probably will hate it. I haven’t told them yet.” Well, you have now.