Credit: Wendie Jo Sperber: Mike Guastella/

You know Wendie Jo Sperber, who lost her battle with breast cancer Tuesday. She was Tom Hanks’ galpal on Bosom Buddies and Marty McFly’s sister in the Back to the Future series, and she popped up in a variety of guest spots on Will & Grace, Murphy Brown, and 8 Simple Rules. Her performances were characterized by her distinctive voice and acerbic delivery, but in life, she aimed for sincerity. After being diagnosed in 1997, she founded weSPARK, a cancer support center in Sherman Oaks, Calif. Hanks said in a statement: “The memory of Wendie Jo is that of a walking inspiration. She met the challenges of her illness with love, cheer, joy and altruism. We are going to miss her as surely as we are all better for knowing her.” Amen, Hanks-y!

addCredit(“Wendie Jo Sperber: Mike Guastella/”)