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Chris Sullivan on This Is Us
Though Toby has long struggled with being overweight, his portrayer Chris Sullivan doesn't have that problem in real life. In fact, the actor wears a fat suit and prosthetics while in character.
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Louie Anderson on Baskets
Anderson nabbed an Emmy nomination for his role as Zach Galifianakis's mother on the FX comedy. Yes, you read that correctly.
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Emilia Clarke on Game of Thrones
When Daenerys Targaryen isn't off being an all-around badass, she's spending time in the costume chair. It takes Emilia Clarke, whose natural hair color is much darker than that of her dragon-slaying counterpart, two hours to nail Daenerys' look.
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Melissa McCarthy as Sean Spicer on SNL
McCarthy has her impeccable Saturday Night Live Spicer impression down pat, from the hilarious wig to the jacket that's juuuust a bit too big.
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Naomi Grossman in American Horror Story: Asylum and Freak Show
To play Pepper, Grossman is outfitted with prosthetic ears, fake eyebrows, a fake nose, fake teeth, and of course, a different hairstyle. You can watch the whole thing go down here.
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Neil Patrick Harris in A Series of Unfortunate Events
Count Olaf is a master of disguise, but even in his natural state, the villain shares hardly any facial features with Neil Patrick Harris.
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Jeffrey Tambor on Transparent
Tambor has won two Emmys for his portrayal of Maura Pfefferman, a retired college professer who comes out to her family as transgender.
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Sarah Paulson in American Crime Story: The People v. O.J. Simpson
Paulson loved the wig she donned to play O.J. Simpson prosecutor Marcia Clark so much, she kept it with her after filming wrapped, bringing it with her on her various travels. She also made sure to wear the same perfume as Clark, an "extremely stinky" scent called Magie Noire.
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Bryan Cranston in Breaking Bad
Cranston goes from terrifying drug kingpin to family-friendly dad-next-door with one cut of the razor.
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Uzo Aduba in Orange Is the New Black
In real life, Aduba's eyes are significantly less crazy than Crazy Eyes', and the braids are nowhere to be found.
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Jimmi Simpson in It's Always Sunny in Philadelphia
Before Simpson was running rampant through Westworld and threatening suicide on This Is Us, he was a milk-chugging, eye patch-wearing McPoyle brother on It's Always Sunny in Philadelphia, unibrow and all.
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Shannon Purser in Stranger Things
The pride and joy of the Stranger Things fandom, Barb looks perfectly normal for a '80s teen. In real life, however, Purser has been known to go in an old Hollywood glam direction, ditching the glasses and plaids for winged eyeliner and red lips.
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Elisabeth Moss in season 1 of Mad Men
Peggy Olson may have concluded Mad Men's seven seasons in sunglasses and roller skates, but she began the series by getting pregnant and not knowing it. You can watch the costume designer and makeup department head talk about transforming the chic Elisabeth Moss in a video here.