Natalie Abrams
August 08, 2017 AT 12:00 PM EDT

To celebrate Fall TV and our huge Fall TV Preview issue — hitting stands on Sept. 15 — EW is bringing you 50 scoops in 50 days, a daily dish on some of your favorite shows. Follow the hashtag #50Scoops50Days on Twitter and Instagram to keep up with the latest, and check EW.com/50-Scoops for all the news and surprises.

Grey Sloan will be rocked by even more family drama when Grey’s Anatomy returns this fall.

EW has learned exclusively that Italian actress Stefania Spampinato has booked a multi-episode arc as the sister of Giacomo Gianniotti’s Andrew DeLuca.

Carina DeLuca will actually take up residence as a new doc at Grey Sloan, which becomes a bit of a nightmare situation of Andrew. “This year, we’re going to definitely have DeLuca’s character a little more fleshed out with the arrival of his sister from Italy,” Gianniotti tells EW. “We’re going to see a new dynamic in the hospital as his sister arrives, and it’s not exactly good news; he’s frustrated by it.”

Susie Delaney; Richard Cartwright/ABC/Getty Images

“She has a very interesting and controversial — some would say — profession within the medical field, which makes him uncomfortable,” Gianniotti continues. “It’s a thorn in his side, her being there, but everybody else is quite fond of her. She will be working [at the hospital], and she’s going to help tell the story of DeLuca and how he comes from Italy. They’re going to speak a little bit of Italian, which will be nice for the Italian fans, because [the show’s] so big in Italy.”

The news comes on the heels of Abigail Spencer joining the cast for a multi-episode arc, replacing Bridget Regan as Owen’s sister Megan Hunt, who has been presumed dead for the last decade.

Grey’s Anatomy will return with a two-hour premiere on Thursday, Sept. 28 at 8 p.m. ET on ABC.

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