The scene that started it all. Barrymore played Woodsboro teen Casey Becker, the first of many to receive a phone call from Ghostface. Casey (and her boyfriend, Steve) were both brutally disemboweled.
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Henry Winkler: Scream
The Fonz played Principal Himbry, who, after punishing two students dressed like Ghostface, met his gory end.
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Rose McGowan: Scream
Poor Tatum Riley was only trying to be helpful and get some more beers for her boyfriend, Stu. But her trip to the garage was her last, as she battled Ghostface and ended up dead in the doggy door.
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Matthew Lillard: Scream
For a killer who watched a ton of horror movies, it was appropriate for Stu to be dispatched by Sidney dropping a TV on his head.
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Skeet Ulrich: Scream
Billy Loomis was not only stabbed with an umbrella by Sidney (who was clad in a Ghostface outfit) he was later shot in the head after he came back to life. They always come back.
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Jada Pinkett: Scream 2
Maureen, a self-admitted EW fan, and boyfriend Phil just wanted a fun night out at the movies. Unfortunately, Ghostface murdered Phil in the men's room and took out Maureen in front of an audience at a Stab screening.
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Sarah Michelle Gellar: Scream 2
Cici was the sober sister at her sorority, so she had to stay home and wait for a drunk sister to call. Ghostface ended up being on the line instead and ultimately threw Cici off the roof of her house.
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Jamie Kennedy: Scream 2
Proving the killers' brutality, fan favorite Randy was knifed in broad daylight after Ghostface grabbed him and stuffed him in one of Gale's production vans.
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Elise Neal: Scream 2
Hallie survived a nasty car accident with Sidney after Ghostface hijacked their ride (and knocked off their police escort). But then Ghostface surprised her with his trusty knife.
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Jerry O'Connell: Scream 2
Derek was tied up by his frat on the theater stage and then got a bullet in the chest from Mickey, one of the two killers.
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Timothy Olyphant: Scream 2
Mickey and Sidney had a massive fight (she sorta kicked his butt), but he eventually got the upper hand. He was ultimately betrayed, and shot, by Mrs. Loomis and shot. He then came back to life and was shot again. Can't blame him for trying.
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Laurie Metcalf: Scream 2
Mrs. Loomis had been telling everyone that she was reporter Debbie Salt, but in fact she was the mastermind behind all the killings. She died after Cotton Weary shot her and then Sidney finished the job with a bullet to her head.
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Liev Schreiber/Kelly Rutherford: Scream 3
The opening sequence found Cotton and his girlfriend, Christine, stabbed by Ghostface in their own Los Angeles apartment.
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Jenny McCarthy: Scream 3
Supposedly meeting director Roman at the production office, Sarah Darling instead found Ghostface, who stabbed her and threw her through a glass partition.
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Matt Keeslar: Scream 3
Tom Prinze was set to play a Dewey rip-off in Stab 3, but he perished when Ghostface blew up Jennifer's house.
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Emily Mortimer: Scream 3
Angelina freaked out at movie producer John Milton's mansion and ran once people started disappearing. Sadly, she ran right into Ghostface's knife.
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Parker Posey: Scream 3
Jennifer thought she'd escaped Ghostface by finding a secret passage in Milton's house. But she was stabbed behind a two-way mirror and discovered by Gale and Dewey.
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Scott Foley: Scream 3
Roman Bridger came clean about being the one behind all these killings, and he and his half sister, Sid, got into quite a tussle. Roman was wearing a bulletproof vest, so he survived various gunshots, but Dewey finally put one in his brain.