More from EW
1 of 20
One of MADtv’s most memorable cast members, Alex Borstein became known for her popular recurring characters such as Mrs. Swan and Eracist Anne. It was there that she met Seth MacFarlane, who was preparing to release Family Guy as a series of animated shorts for MADtv. The collaboration fell through, but Borstein stayed on as the voice of Lois Griffin. Since leaving MADtv in the 2000s, Borstein has booked gigs in The Lizzie McGuire Movie, Ted, and Gilmore Girls, and made a more dramatic turn in Good Night, and Good Luck . She most recently starred as Dawn in HBO's Getting On.
2 of 20
During his time on MADtv, Barinholtz was one of the more popular cast members thanks to characters like Abercrombie & Fitch model Dutch and his celebrity impersonations. In 2007, he left the show and has since appeared in 2015's Sisters, Eastbound & Down in 2012, and 2014's Neighbors. He is perhaps best known for his main role of Morgan Tookers on The Mindy Project, and will appear in Suicide Squad.
3 of 20
Sullivan was an original MADtv cast member, and introduced several characters during her six seasons on the show. Her most popular character was the emotionally abusive Vancome Lady, who appeared in the very first episode of MADtv. Sullivan has been a television staple in the years since she left the show, making mid-2000s appearances on The King of Queens, Raines, Scrubs, and Rita Rocks, and lending her voice to Kim Possible, Family Guy, and, in 2014, BoJack Horseman.
4 of 20
MADtv was already well-established when a then-unknown Keegan-Michael Key was cast for the show’s ninth season. Key's turn on the sketch show was notable for his character of the enraged Coach Hines, and for his various celebrity impersonations. After MADtv, Key formed his currently running sketch-comedy show Key & Peele with his former castmate Jordan Peele. He’s also had many movie and TV roles, such as Due Date (2010), The Lego Movie (2014), and recent turns on Playing House, Parks and Recreation, and Fargo.
5 of 20
Thanks to Key & Peele, Jordan Peele is now heavily associated with Keegan-Michael Key in the public eye. Years earlier, the two actors actually auditioned against each other for MADtv, but both were cast in 2004 due to their undeniable chemistry. Like Key, Peele has found acting success after MADtv as well, booking roles in Little Fockers (2010) and Wanderlust (2012), and hitting the small screen in Fargo and Kroll Show in 2014, and Life in Pieces in 2015.
6 of 20
Mo Collins joined MADtv in in 1998, and quickly became a fan favorite for her characters of Lorraine, Trina, and Stuart’s mother Doreen. Collins had a recurring role as Starla in Arrested Development in the mid-2000s and picked up small roles in the Judd Apatow movies The 40-Year-Old Virgin (2005) and Knocked Up (2007). Most recently, she portrayed the popular recurring character Joan Callamezzo in Parks and Recreation.
7 of 20
Michael McDonald may have had the most time on MADtv of any cast member, but Debra Wilson is the original star to last the longest — eight seasons in total. Wilson was well-known during her tenure for her character Bunifa Latifah Halifah Sharifa Jackson and for her impression of Oprah Winfrey. Wilson went on to appear in Avatar in 2009, 2 Broke Girls in 2013, and lent her voice to episodes of Family Guy and The Cleveland Show.
8 of 20
Michael McDonald may be the face most associated with the show for viewers. His decade on MADtv was marked by a number of popular recurring characters, including Stuart, Bible Dude, and Rusty Miller to name a few. McDonald went on to write, direct, produce, and appear in the ABC series Cougar Town and write and star in a handful episodes of Scrubs. He recently hit the big screen in two Paul Feig films: The Heat (2013) and Spy (2015).
9 of 20
Before joining MADtv in 2005, Myrin had appeared in guest spots on a few big network sitcoms, like Friends and Working . She stayed on the show until its cancellation in 2009, and went on to frequently serve as a panelist on Chelsea Lately. She continued her acting career with roles in Morning Glory (2010) and Bachelorette (2012) and picked up arcs on Suburgatory, Psych, and Fresh Off the Boat in recent years.
10 of 20
Lee was one of the most prolific cast members on MADtv, appearing on the show for eight seasons. He’s made several television appearances since leaving MADtv, including Animal Practice and The League, and acted in high-profile comedies such as Pineapple Express (2008) and Harold & Kumar Go to White Castle (2004).
11 of 20
One of the original MADtv cast members, LaMarr introduced characters such as Savante and Desperation Lee in addition to an extensive list of celebrity impressions. LaMarr was already a veteran actor when he joined the show, with roles in The Fresh Prince of Bel-Air, Pulp Fiction, and The George Carlin Show already to his name. Since leaving the show, LaMarr has focused largely on voice acting, including turns as the voice of Samurai Jack in Samurai Jack in the early 2000s, Hermes in Futurama throughout the 2000s, and the Green Lantern in Justice League in the mid-2000s.
12 of 20
Weir’s six-year tenure on MADtv is remembered for her characters of Dot Goddard and Angela Wright, among others. She went on to serve as a writer and consulting producer for two sitcoms: Raising Hope and The Millers. She also starred in FX show The Comedians, and picked up bit roles in Modern Family (2011), and Playing House, Crazy Ex-Girlfriend, and Life in Pieces in 2015.
13 of 20
Spears was another cast member with a good amount of exposure before joining MADtv. Ahead of his first appearance in 1997, Spears already had credits for Jerry Maquire (1996) and South of Sunset (1993). In the years since he left MADtv in 2005, Spears has picked up small screen roles in Showtime's The Underground, CSI: Miami, and TripTank.
14 of 20
Flanagan was on MADtv for five seasons in the late 2000s, and made a name for herself with characters like stand-up comic Luann Lockhart and QVC host Christie. Aside from MADtv, Flanagan is most known for her recurring role as Lois Salder on Mad Men, and late 2000s parts in Hank and The New Adventures of Old Christine. She’s recently had guest spots on TV comedies, such as Workaholics, Marry Me, and Trophy Wife.
15 of 20
Artie Lange may have only been on MADtv for the show’s first two seasons, but he became one of the its most infamous alums. A well-known struggle with substance abuse had an influence on Lange's career, and was detailed in the actor's 2013 memoir, Crash and Burn. He continued his comedy work after MAD, with the release of albums and podcasts and a gig on The Howard Stern Show, and made big-screen appearances in Mystery Men (1999), Old School and Elf in 2003, and Beer League in 2006. His recent credits include roles on Louie and Inside Amy Schumer.
16 of 20
Anjelah Johnson actually only appeared in a few episodes of MADtv , but she used that very brief spotlight to deliver two of the most memorable characters: her Vietnamese nail technician character and the fast food worker Bon Qui Qui. Since she left the show, Johnson has debuted stand-up specials, released an EP and an album as her character Bon Qui Qui, and made appearances in Ugly Betty (2010), Curb Your Enthusiasm (2011), and Enough Said (2013).
17 of 20
Daly joined MADtv for two seasons, and although his characters and impressions earned some acclaim, it wasn’t until after he left the show in 2002 that his career began to take off. Daly went on to become a go-to actor in the comedy world, appearing in Reno 911, Eastbound & Down, Silicon Valley, and Comedy Bang! Bang!. Since 2014, Daly has helmed Comedy Central’s critically acclaimed mockumentary series Review, and picked up roles in Black-ish, Adventure Time, and Grandfathered.
18 of 20
Before he got the part of the turtleneck-loving nerd Howard Wolowitz on The Big Bang Theory, Simon Helberg appeared in various episodes of MADtv. He went on to star in Derek & Simon projects along with Derek Waters and had notable roles in Studio 60 on the Sunset Strip, Dr. Horrible’s Sing-Along Blog, and A Cinderella Story in the 2000s.
19 of 20
For six seasons, Parker made use of both her musical theater and comedy talents on MADtv by doing impressions of famous singers and incorporating song into original characters like the Disney Girl and Pat-Beth LaMontrose. Parker performed as Elphaba in Wicked on Broadway in 2009 and reprised the role in the musical's first North American tour in 2012. Her recent onscreen roles include episodes of Key and Peele and Hot in Cleveland.
20 of 20
Most fans know Taran Killam from his current gig on Saturday Night Live, but he refined his comedy chops with a one-season stint on MADtv back in 2001. Only 19 at the time, Killam was the youngest cast member, though he already had roles in Judging Amy, Touched by an Angel, and Roswell to his name. Before landing his spot on SNL, Killam appeared in Nick Cannon Presents: Wild 'N Out, Just Married, and My Best Friend's Girl. He also made a dramatic turn in 2013's critically acclaimed 12 Years a Slave.