1 of 8
After picking up early credits in TV movies and videos, Hilary Duff hit the small screen in Lizzie McGuire in 2001, leading the series as its title teenage girl. Duff played McGuire for the length of the show's three-year run, going on to expand her résumé with big-screen turns in A Cinderella Story, Raise Your Voice, The Perfect Man, Material Girls, War, Inc., Stay Cool, and What Goes Up, as she continued her music career, racking up four studio albums. In recent years, Duff returned to music with 2015's Breathe In. Breathe Out., had a six-episode arc on Gossip Girl, and starred in Younger as Kelsey Peters.
2 of 8
Lalaine starred opposite Duff as Lizzie McGuire's best friend, Miranda Sanchez. The actress, who got her start in TV movies, made an appearance in two episodes of Buffy the Vampire Slayer during Lizzie McGuire's run, also dropping her own studio album and EP during that time. After saying goodbye to Miranda, Lalaine earned credits for Her Best Move, Easy A, and episodes of Off the Clock.
3 of 8
Adam Lamberg rounded out Lizzie McGuire's main trio as Gordo. The actor, who earned prior credits for I'm Not Rappaport and Max Keeble's Big Move, played Lizzie's pal for three years, also starring alongside the gang in 2003's The Lizzie McGuire Movie. Lamberg wrapped his on-screen career soon after, picking up his final roles in 2005's When Do We Eat? and the 2008 indie Beautiful Loser. The former child star went on to attend University of California, Berkeley and now works for the Irish Arts Center in New York City.
4 of 8
Hallie Todd joined Lizzie McGuire as Lizzie's mom, Jo McGuire. She came into the part after racking up roles in Brothers, Going Places, Murder, She Wrote, and Life with Roger. While she took a bit of a break from her acting career, Todd recently appeared in the American Girl video Lea to the Rescue and is expected to appear in the upcoming drama The Last Champion.
5 of 8
After appearing in The Cowboys, Orca, Coming Home, The Long Riders, The Big Red One, and Revenge of the Nerds, Robert Carradine played Lizzie's father, Sam McGuire, in Lizzie McGuire. After wrapping his run on the show, Carradine earned additional credits for Supercross, Tooth and Nail, Sex and Breakfast, and Django Unchained.
6 of 8
Lizzie McGuire found its Matt McGuire in child star Jake Thomas. He played Lizzie's little brother after popping up in episodes of 3rd Rock from the Sun and Touched by an Angel, and playing Martin Swinton in A.I. Artificial Intelligence. Thomas went on to appear in episodes of The Grim Adventures of Billy & Mandy, Cory in the House, Cold Case, House, Ghost Whisperer, and Criminal Minds.
7 of 8
Ashlie Brillault made her on-screen debut as Lizzie McGuire's Kate Sanders, the school's resident popular girl. During the show's run, she hit the big screen in The Lizzie McGuire Movie and appeared in an episode of One on One. She ended her acting career in 2004, turning her focus to law. Brillault earned a law degree from the University of Denver and went on to pursue a career in the field.
8 of 8
Clayton Snyder had a memorable turn in Lizzie McGuire as school hottie Ethan Craft. Snyder took a few years off after his debut role to attend high school and college, returning to acting in recent years with gigs in NCIS, Rules of Engagement, Hit Women, and Edgar Allan Poe's Murder Mystery Dinner Party.