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Christina Yang on Grey's Anatomy
Undeniably sexy in Sideways, the Canadian actress is now one of the most reliably awesome parts of Grey's Anatomy. As the hyper-competitive doc Christina Yang, Oh stirs things up week after week with her unique brand of Type-A comeliness.
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MARY LYNN RAJSKUB
Chloe O'Brien on 24
What would C.T.U. be without the sardonic, deadpan wit of Rajskub's Chloe O'Brien? A soul-sucking haven of stressed-out, asocial tech geeks tapping on keyboards, that's what. So thanks for being the only female regular on the show, Mary Lynn.
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Zoe in Fanboys
With Veronica Mars, Forgetting Sarah Marshall, even Heroes, we already knew Bell was hot. But in Fanboys, she dressed up as ''slave'' Leia, so...geek!
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Rachel on Glee
As the aggressively ambitious Rachel on Glee, Michele takes what could be an abrasive stereotype and makes it a thing of beauty.
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Hermoine Granger in the Harry Potter films
Know-it-all Hermione not only adds some much needed feminine energy to the Harry Potter franchise but also proves that, in real life and at Hogwarts, girls are just as good as boys. Especially when it comes to magic.
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Codex in The Guild
Dr. Horrible's Sing-Along Blog + The Guild + Dollhouse's ''Epitaph One'' = Geekalicious
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Holly in Land of the Lost
As Will Ferrell's paleontologist's assistant who also ends up making out with her boss, Friel executes such geeky tasks as repairing an amplifier, receiving a holographic message from the Zam, and wearing an updated lady-version of young Holly's outfit from the original 1974 TV series. (Plus, one could argue that Pushing Daisies catered to a certain type of TV Geek, and we loved her in that.)
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Astrid Farnsworth on Fringe
Her junior FBI agent might spend most of her time stuck in a musty basement laboratory with the mad genius Dr. Walter Bishop (John Noble), helping with way-out experiments on cows, rats, and human beings, but hey, if it helps her maintain her trademark ethereal glow, then we're all in favor.
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PJ on My Boys
PJ can throw down with baseball stats, hold her own in a beer-guzzling contest, and host a killer poker night — but she's so much more than one of the guys.
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Wendy Watson on The Middleman
You have to be pretty badass to solve ''exotic problems'' — like alien invasions and supernatural villains — by day and manage a pretty cool early-20s social life by night, but somehow Wendy ''Dub Dub'' Watson made it look easy.
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Temperence ''Bones'' Brennan on Bones
Leave it to someone named Temperance to make us go wild. Dr. Temperance ''Bones'' Brennan makes borderline catatonia seem hot, from her furrowed brow to the tips of her latex-gloved fingers — even if they're probing around a grody corpse. Talk about brains and beauty.
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Hostess of Attack of the Show
Pretty women are a dime a dozen in Los Angeles — we're pretty sure California scientists have perfected the botanical genealogy that would allow them to actually be harvested from trees. But knockouts that can drop Star Wars science at the drop of a hat, expose their fear and hatred of balloons to millions, and dive arse-first into giant pies — no, those are a rare breed, indeed. A grateful nation thanks your parents, Olivia Munn. And we thank you, too.
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