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Angelina Jolie and Brad Pitt
The actors “fell in love” on the set of Mr. & Mrs. Smith in 2005, according to Jolie. Pitt and ex-wife Jennifer Aniston officially divorced that year as news of his relationship with Jolie made headlines. The two were married in 2014, and have six children together: Maddox, Pax, Zahara, Shiloh, Vivenne, and Knox. Jolie and Pitt teamed back up on the big screen in 2015, starring together in By the Sea. News broke in September 2016 that the two stars were parting ways after Jolie filed for divorce from Pitt. “Angelina Jolie Pitt has filed for dissolution of the marriage. This decision was made for the health of the family. She will not be commenting at this time, and asks that the family be given their privacy during this difficult time,” Jolie’s attorney said in a statement to PEOPLE.
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Alicia Vikander and Michael Fassbender
Alicia Vikander and Michael Fassbender hit the big screen together in The Light Between Oceans Friday, a film that was shot while the two actors fell in love. The Oscar-winning Danish Girl actress and the Oscar-nominated Steve Jobs star started dating in 2014 as they worked on the romantic drama, an adaptation of M. L. Stedman's novel of the same name. The two, who attended awards shows arm-in-arm earlier this year, touched on their relationship in an August interview with EW. "It wasn’t the first time in a movie either of us had played somebody who is falling in love. There is an element of separation there. If I’m playing a murderer, I don’t go out and start murdering people," Fassbender said of their work on The Light Between Oceans, while Vikander weighed in, "I think we’ve made a clear statement that we keep certain things just between us. It was very easy to unite, but that’s quite personal."
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Anna Camp and Skylar Astin
Pitch Perfect costars Anna Camp and Skylar Astin didn’t play love interests in the 2012 a cappella movie, but sparks still flew. The pair began dating in June 2013 and announced their engagement the following January. Camp and Astin, who both returned for Pitch Perfect 2, had an aca-amazing joint bachelor-bachelorette party in August 2016 complete with line-dancing, fellow Pitch Perfect star Brittany Snow, and adorable Instagrams to document the weekend.
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Jennifer Aniston and Justin Theroux
Wanderlust co-stars Theroux and Aniston began dating in 2011, and got engaged in 2012 before making it official in August 2015 during a small ceremony at their California home.
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Halle Berry and Olivier Martinez
Halle Berry met her third husband, Olivier Martinez, when the two filmed 2012's Dark Tide together. The actress played a shark diver named Kate, while Martinez was Kate's business-minded ex-boyfriend. The two stars tied the knot in July 2013, but split two years later, announcing their divorce in October 2015. "It is with a heavy heart that we have come to the decision to divorce," the couple said in a joint statement to People at the time. "We move forward with love and respect for one another and the shared focus of what is best for our son. We wish each other nothing but happiness in life and we hope that you respect our and, most importantly, our children's privacy as we go through this difficult period."
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Jennifer Garner and Ben Affleck
The two first met on the set of Pearl Harbor back in 2001, and would work together again two years later on the superhero flick Daredevil. Affleck and Garner were married in 2005 and would go on to have three children: Violet, Seraphina, and Samuel. They announced their split in June 2015 after 10 years together.
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Alexis Bledel and Vincent Kartheiser
The Mad Men co-stars first made their relationship public back in Oct. 2012 and were engaged just a few months later in Feb. 2013. Of course, Bledel’s Gilmore Girls’ TV mom (Lauren Graham) gave the seal of approval saying she was “very happy for them.” The two made it official in June 2014, saying “I do” during a small ceremony in California.
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Anna Paquin and Stephen Moyer
The Oscar-winning actress met her husband on the set of HBO’s vampire drama True Blood as the two played on-again-off-again love interests Sookie Stackhouse and Bill Compton. After a year-long engagement, they were married in Aug. 2010. They have two children together: Twins Charlie and Poppy.
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Sarah Michelle Gellar and Freddie Prinze Jr.
Nothing like a teen horror flick to bring two kids together. Sarah Michelle Gellar and Freddie Prinze Jr. met on the set of I Know What You Did Last Summer in 1997 and would tie the knot in 2002. But, they would reunite on-screen for two Scooby-Doo films: 2002’s Scooby-Doo and 2004’s Scooby-Doo 2: Monsters Unleashed. Today, the pair are still happily married and have two children: Charlotte and Rocky.
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Kelly Ripa and Mark Consuelos
Love bloomed on the set of the soap All My Children, as on-screen love interests Kelly Ripa and Mark Consuelos carried their romance off-screen. After dating for a year, the two were married in 1996. The actors have three children together: Michael, Lola, and Joaquin.
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Channing Tatum and Jenna Dewan
The Step Up co-stars found love on the dance floor when they starred as on-camera love interests back in 2006 and were officially wed in 2009. They welcomed their first child, Everly, in 2013.
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Emma Stone and Andrew Garfield
The young lovebirds met on the set of the superhero reboot The Amazing Spider-Man, as Stone played the role of Gwen Stacy to Garfield’s Spider-Man. While the media speculated the two were taking a break back in April 2015, Stone told the WSJ, the relationship with Andrew was “so special” to her which is why she avoids talking about it publically.
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Mila Kunis and Ashton Kutcher
Kunis and Kutcher first met on the set of the popular sitcom That ‘70s Show, but wouldn’t officially start dating until 2012 – Kutcher was previously married to actress Demi Moore for eight years. They were engaged in 2014 and welcomed their first child, Wyatt, in Oct. 2014. The stars reportedly tied the knot over the Fourth of July weekend this year.
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Goldie Hawn and Kurt Russell
The pair met on the set of Disney’s 1968 film The One and Only, Genuine, Original Family Band, but didn’t begin dating until 15 years in 1983 when the two reconnected while filming Swing Shift. The actress reportedly opened up to Porter magazine in June of 2015 about her relationship with Russell and why the two never decided to wed. Hawn told the magazine, “a lasting relationship isn’t about marriage” but rather “compatibility and communication.” They have one child, Wyatt, together.
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Ginnifer Goodwin and Josh Dallas
Goodwin and Dallas found happily ever after on the set of Once Upon a Time, acting opposite each other as Snow White and Prince Charming. The show premiered in 2011, with actors officially tying the knot in April 2014. They welcomed a son, Oliver, a month later in May.
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Michael J. Fox and Tracy Pollan
The two stars met on the set of Family Ties in the 1980s. In their twenties at the time, Fox and Pollan did not begin dating right away, despite their on-screen relationship as Alex P. Keaton and his girlfriend Ellen Reed. After ending her romance with Kevin Bacon, Pollan started things up with Fox and the two tied the knot in 1988. The former costars have been married for more than 25 years and have four children together.
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Kaley Cuoco and Johnny Galecki
Cuoco and Galecki met on the set of The Big Bang Theory and quietly started dating in the late 2000s. The two costars, who play TBBT couple Penny and Leonard, parted ways after two years together. Rumor spread in October 2015 that the actors rekindled their romance following Cuoco's split from Ryan Sweeting, but she shared an Instagram photo with Galecki to quiet the chatter. "So sorry to disappoint, but no home wreckers or secret flings going on here," she captioned the shot. "Me and @sanctionedjohnnygalecki are just the best of buds — Leonard and Penny will just have to suffice!"