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Masters of Sex not returning for a fifth season

The Showtime series aired its final episode on Nov. 13

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Warren Feldman/SHOWTIME

The lessons are over. Masters of Sex has concluded its run as Showtime has opted not to renew the period drama for a fifth season, EW has confirmed.

The fourth season of Michelle Ashford’s drama concluded on Nov. 13, fittingly ending with William Masters (Michael Sheen) and Virgina Johnson (Lizzy Caplan) tying the knot.

Masters of Sex was a beautifully writen and acted exploration of America’s changing sexual mores,” Showtime said in a statement. “We are incredibly proud to have shared the story of Masters and Johnson for four critically-acclaimed seasons. The series will remain available across our platforms where new viewers can discover it for years to come.”

Debuting in 2013, Masters of Sex was loosely based on Thomas Maier’s biography of the duo, who served as pioneers in the research of human sexuality. The series began in the 1950s, before moving into the ‘60s, and finally, in season 4, to the much more progressive ‘70s.

Over its run, the drama earned 10 Emmy nominations, including three nominations and one win for Allison Janney for Outstanding Guest Actress in a Drama Series for her portrayal of Margaret Scully, wife to Masters’ closeted gay mentor.

Deadline first reported the news.