ABC
Christian Holub
February 26, 2016 AT 01:30 PM EST

Jimmy Kimmel once again deployed his signature bit, Mean Tweets, on Thursday’s episode of Jimmy Kimmel Live! In honor of Sunday’s Oscars, the movie-themed edition featured A-list film stars.

Many of this year’s Oscar nominees took a turn in the hot seat, such as Eddie Redmayne (“‘Eddie Redmayne looks like someone tried to erase his nose, but couldn’t completely. I also think he looks perpetually dehydrated”) and Cate Blanchett (“Cate Blanchett f—ing play-doh looking face uggo”). 

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Other highlights included George Clooney (“If that gross ratty old man George Clooney can find a girl…you regular fellas out there in the twitterverse must be drowning in p—y”) and Oscar Isaac (“Oscar Isaac is a Brooklyn hipster piece of s— and I’m gonna fight him”). Emily Blunt’s started well but quickly took a turn for the worse (“Emily Blunt’s got a purdy mouth…that I’d like to poop in”). The most intricate insult of all, though, was reserved for Sean Penn: “Sean Penn: 1) has a penis nose, 2) has a scrotum face, 3) has an anus mouth, 4) is a butthole.”

Watch the full clip below.

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