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'Neighbors' trailer: 'You guys just woke a sleeping giant' -- VIDEO

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What goes well with a house full of 50 fraternity brothers? Well, other than booze, hazing, and women … not much.

In the newest trailer for Neighbors, Seth Rogen and Rose Byrne play a quiet married couple who spend their days dressing their daughter up as TV characters for a calendar shoot. But when a fraternity moves in next door, their lives become a lot less about calendars and a lot more about parties, pranks, and one very unfortunate incident involving a condom. With Zac Efron and Dave Franco as neighbors, things are about to get a little crazy.

Watch the latest trailer below:

Neighbors hits theaters May 9, 2014.