Late last night, Oprah Winfrey tweeted that she will be announcing her new Book Club selection on Friday, Sept. 18 and that she’s “never made a selection like ‘this’.” Ron Hogan at MediaBistro’s GalleyCat blog has already begun snooping on Amazon and BN.com to guess the title based on his knowledge of the publisher (Little, Brown) and the suggested retail prices ($23.99 in hardcover and $14.99 in trade paperback). His best guesses: James Collins’ 2008 debut novel Beginner’s Greek and Uwem Akpan’s remarkable 2008 story collection Say You’re One of Them (which EW’s Jennifer Reese ranked the best fiction title of last year). Akpan, a Nigerian-born priest who writes eloquently and movingly about the harrowing effects of AIDS and genocide on Africa, would seem to be a perfect author for Winfrey given her long-standing interest in the continent. (She has opened two schools for South African youth.) One thing’s for sure: The folks at Little, Brown, which is anomalously flush as the publisher of Stephenie Meyer, must be very happy campers.