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Kathy Griffin: Live from Madison Square Garden

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What do Jessica Simpson, Sarah Palin and an 88-year-old who loves a box of wine have in common? They were all fodder for Kathy Griffin last night, who performed at the WaMu Theater at Madison Square Garden to a full-capacity crowd that included financial rockstar Suze Orman (sixth row center, natch—after all, she appeared on Griffin’s show, My Life on the D-List, last season). Among her best material:

On her New Year’s Eve brouhaha with Anderson Cooper: “What happened was as the night got longer, we got slaphappy.… We were cold and I was just trying to make him laugh. So someone said we had gone to commercial and I said, [to Anderson] ‘I don’t go to your job and knock the d—s out of your mouth’… It’s the second standard old comedy club line to hecklers.”

On Jessica Simpson: “If she doesn’t get the gastric bypass SHE COULD DIE… Jessica Simpson is twice the size of Ruby from The Style Network.”

On Miley Cyrus’ Vanity Fair photo shoot with her dad: “If I had a picture of me [like that] with my dad, may he rest in peace, we’d both be vomiting.”

On Sarah Palin: “I miss Palin, because, as a comedian, it would almost be like having Vice President Paula Abdul.”

On winning her second trophy at the Creative Arts Emmy Awards: “It’s me against the guy who puts out the carrots for Two and a Half Men

On her mom: “I got her to vote for Obama and there may or may not have been a box of wine involved.”

On her mother part  2: “My mother moved out. You know why? Because she finds me annoying”

What do you think? Do you agree with Kathy’s mom? Or do you totally dig her like the crowd did last night? And most importantly, are you psyched for Life on the D-List, which Griffin says will premiere on Bravo this summer?