Chris Haston
EW Staff
March 09, 2008 AT 05:00 AM EDT

9-10PM · NBC · Returns Sept. 22

Season 3 will open by revealing who shot Nathan Petrelli (Adrian Pasdar) — and then immediately launch into brand-new stories. Hiro (Masi Oka) inherits a DVD from his father, charging him to safeguard a mysterious formula from evildoers, and Peter Petrelli (Milo Ventimiglia) goes MIA, only to be replaced by…his future self from the year 2012. As for the overarching theme, this volume ”unleashes a cadre of villains into the world that have to be stopped,” says creator Tim Kring. ”Battle lines are drawn, and some of our characters choose the wrong side.”

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