”It’s about fathers and sons, mothers and daughters, brothers and sisters, about the enemies lurking in the bosom of the family,” says producer-writer Akiva Goldsman — and he ain’t talking about Anna Karenina. Like every other schlocky TV show from the ’60s, Lost in Space, which ran on CBS from 1965 to 1968, is getting a big-screen makeover, but don’t expect any papier-mache rocket ships or aliens with visible zipper lines. The $70 million effects-packed Event Flick, filmed in London this summer, shows shocking signs of intelligent life. Take the casting: William Hurt (Michael) stars as astronaut dad John Robinson and Mimi Rogers (The Mirror Has Two Faces) is his biochemist wife, Maureen. There’s also Heather Graham (Boogie Nights) and Lacey Chabert (Party of Five) as daughters Judy and Penny, and Jack Johnson as son Will Robinson (”I won’t be as wimpy as the kid on the TV show,” he promises). Friends‘ Matt LeBlanc plays Maj. Don West, and perennial nutcase Gary Oldman takes on that classic small-screen villain, Dr. Zachary Smith (”a bit like Richard III,” he describes the character). The Robot, incidentally, is being played by himself, with help from the puppet masters at Jim Henson’s Creature Shop. Expect the Jupiter 2 crew to land in theaters April 3.